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Brain death and organ transplantation

Brain death is an irreversible extinction of all brain functions including brainstem functions despite of the working cardiovascular system or other organs. The organ donor can be living human or the organ can be taken from the body of dead one. The condition is free and voluntary donor decision. The dead donor is in most cases a person, whose brain damage leads to its death, which  has to be medicaly very precisely examinated and confirmed by objective screening procedure.

Author: Peter Kľúčovský, MD, Návoj Michal, Šaffo Matúš

Institution: Faculty of Medicine at Masaryk University in Brno

Medical discipline: Emergency Medicine

Keywords: brain death | transplantation | care of organ donor | contraindication | apnea test | verification | confirmation

Educational evel: Undergraduate level | Graduate

Brain death is an irreversible extinction of all brain functions including brainstem functions despite of the working cardiovascular system or other organs. The organ donor can be living human or the organ can be taken from the body of dead one. The condition is free and voluntary donor decision. The dead donor is in most cases a person, whose brain damage leads to its death, which  has to be medicaly very precisely examinated and confirmed by objective screening procedure.


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Review

The algorithm shows the problems of the brain death diagnosis and the indication for the organ removal from the donor in a very clear and comprehensible form. The introductory part discusses in detail the crucial aspects of clinical diagnosis of brain death, as well as its subsequent verification by imaging or electrophysiological methods. This procedure clearly shows both the autonomy of competent doctors in the diagnosis of brain death, as well as the necessary early and a close co-operation with the transplant coordinators. There is also mentioned a need of the hightquality donor care from the diagnosis of brain death to the time of organ removal.
Throughout the algorithm, there is emphasis placed on the basic medical, legislative and ethical principles in a coherent chain of time. This is why can be the algorithm  used not only for teaching but also as a brief manual in common clinical practice. In conclusion, I would like to congratulate and thank the authors for their exact work on the issue of brain death.

publikováno: 1.6.2018 | last modified on: 1.6.2018