Toxic shock syndrome

Author: Tamara Skříšovská, Petr Štourač, Madita Binder

Institution: Faculty of Medicine at Masaryk University in Brno

Medical discipline: Emergency Medicine

Keywords: toxic shock | sepsis | microbiology | antibiotcs | shock managment

Educational evel: Undergraduate level | Graduate

Septic shock is a life threatening condition which needs quick intervention. The treatment and differential diagnosis of septic shock might appear to be quite challeging, but is essential for an optimal outcome for the patient. This algorithm will give a insight into the managment of septic shocks, the differential diagnosis, possible error sources in the diagnosis and characteristics of microbes, that cause shock.

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Toxic shock syndrome is a life-threatening febrile illness that results from a systemic immune response to exotoxins (superantigens) produced most commonly by Staphylococcus aureus. The algorithm describes the most common clinical manifestations, possibilities of differential diagnosis and through correct and incorrect answers the principles of antimicrobial therapy of this disease. This correctly includes a bactericidal antibiotics and bacteriostatic antibiotic, that suppresses toxin production by inhibiting proteosynthesis. This algorithm includes microbiological insights e.g. the principles of correct collection of blood cultures and microscopic and culture image of the bacterium Staphylococcus aureus. The algorithm is a actual and well-created teaching aid.

publikováno: 5. 6. 2021 | last modified on: 28. 9. 2021